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Rictor/mTORC2 involves mitochondrial function in ES cells derived cardiomyocytes via mitochondrial Connexin 43

Rictor is a key component of the mammalian target of rapamycin complex 2 (mTORC2) and is required for Akt phosphorylation (Ser473). Our previous study shows that knockdown of Rictor prevents cardiomyocyte differentiation from mouse embryonic stem (ES) cells and induces abnormal electrophysiology of...

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Detalles Bibliográficos
Autores principales: Wang, Jia-dan, Shao, Ying, Liu, Dan, Liu, Nuo-ya, Zhu, Dan-yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8563760/
https://www.ncbi.nlm.nih.gov/pubmed/33547375
http://dx.doi.org/10.1038/s41401-020-00591-3