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Rictor/mTORC2 involves mitochondrial function in ES cells derived cardiomyocytes via mitochondrial Connexin 43
Rictor is a key component of the mammalian target of rapamycin complex 2 (mTORC2) and is required for Akt phosphorylation (Ser473). Our previous study shows that knockdown of Rictor prevents cardiomyocyte differentiation from mouse embryonic stem (ES) cells and induces abnormal electrophysiology of...
Autores principales: | Wang, Jia-dan, Shao, Ying, Liu, Dan, Liu, Nuo-ya, Zhu, Dan-yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Nature Singapore
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8563760/ https://www.ncbi.nlm.nih.gov/pubmed/33547375 http://dx.doi.org/10.1038/s41401-020-00591-3 |
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