Loss of 15-lipoxygenase disrupts T(reg) differentiation altering their pro-resolving functions

Regulatory T-cells (T(regs)) are central in the maintenance of homeostasis and resolution of inflammation. However, the mechanisms that govern their differentiation and function are not completely understood. Herein, we demonstrate a central role for the lipid mediator biosynthetic enzyme 15-lipoxyg...

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Detalles Bibliográficos
Autores principales: Marques, Raquel M., Gonzalez-Nunez, Maria, Walker, Mary E., Gomez, Esteban A., Colas, Romain A., Montero-Melendez, Trinidad, Perretti, Mauro, Dalli, Jesmond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8563763/
https://www.ncbi.nlm.nih.gov/pubmed/34040168
http://dx.doi.org/10.1038/s41418-021-00807-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8563763/
https://www.ncbi.nlm.nih.gov/pubmed/34040168
http://dx.doi.org/10.1038/s41418-021-00807-x

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