A pre-formulation study of tetracaine loaded in optimized nanostructured lipid carriers

Tetracaine (TTC) is a local anesthetic broadly used for topical and spinal blockade, despite its systemic toxicity. Encapsulation in nanostructured lipid carriers (NLC) may prolong TTC delivery at the site of injection, reducing such toxicity. This work reports the development of NLC loading 4% TTC....

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Detalles Bibliográficos
Autores principales: Castro, Simone R., Ribeiro, Lígia N. M., Breitkreitz, Márcia C., Guilherme, Viviane A., Rodrigues da Silva, Gustavo H., Mitsutake, Hery, Alcântara, Ana C. S., Yokaichiya, Fabiano, Franco, Margareth K. K. D., Clemens, Daniel, Kent, Ben, Lancellotti, Marcelo, de Araújo, Daniele R., de Paula, Eneida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8563806/
https://www.ncbi.nlm.nih.gov/pubmed/34728779
http://dx.doi.org/10.1038/s41598-021-99743-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8563806/
https://www.ncbi.nlm.nih.gov/pubmed/34728779
http://dx.doi.org/10.1038/s41598-021-99743-6

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