Cargando…

A pre-formulation study of tetracaine loaded in optimized nanostructured lipid carriers

Tetracaine (TTC) is a local anesthetic broadly used for topical and spinal blockade, despite its systemic toxicity. Encapsulation in nanostructured lipid carriers (NLC) may prolong TTC delivery at the site of injection, reducing such toxicity. This work reports the development of NLC loading 4% TTC....

Descripción completa

Detalles Bibliográficos
Autores principales:	Castro, Simone R., Ribeiro, Lígia N. M., Breitkreitz, Márcia C., Guilherme, Viviane A., Rodrigues da Silva, Gustavo H., Mitsutake, Hery, Alcântara, Ana C. S., Yokaichiya, Fabiano, Franco, Margareth K. K. D., Clemens, Daniel, Kent, Ben, Lancellotti, Marcelo, de Araújo, Daniele R., de Paula, Eneida
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8563806/ https://www.ncbi.nlm.nih.gov/pubmed/34728779 http://dx.doi.org/10.1038/s41598-021-99743-6

Ejemplares similares

Docetaxel Loaded in Copaiba Oil-Nanostructured Lipid Carriers as a Promising DDS for Breast Cancer Treatment
por: de Carvalho, Fabiola Vieira, et al.
Publicado: (2022)

Mucoadhesive, Thermoreversible Hydrogel, Containing Tetracaine-Loaded Nanostructured Lipid Carriers for Topical, Intranasal Needle-Free Anesthesia
por: Calixto, Giovana Maria Fioramonti, et al.
Publicado: (2021)

Hybrid nanofilms as topical anesthetics for pain-free procedures in dentistry
por: Ribeiro, Lígia N. M., et al.
Publicado: (2020)

Improved Local Anesthesia at Inflamed Tissue Using the Association of Articaine and Copaiba Oil in Avocado Butter Nanostructured Lipid Carriers
por: Rodrigues da Silva, Gustavo Henrique, et al.
Publicado: (2023)

Antineoplastics Encapsulated in Nanostructured Lipid Carriers
por: Rodrigues da Silva, Gustavo Henrique, et al.
Publicado: (2021)

Nanohybrid hydrogels designed for transbuccal anesthesia
por: Ribeiro, Lígia Nunes de Morais, et al.
Publicado: (2018)

Development of a Mosquito Repellent Formulation Based on Nanostructured Lipid Carriers
por: Abrantes, Daniele Carvalho, et al.
Publicado: (2021)

Nanostructured Lipid Carriers for the Formulation of Topical Anti-Inflammatory Nanomedicines Based on Natural Substances
por: Ferreira, Kézia Cristine Barbosa, et al.
Publicado: (2021)

Mechanism of Tetracaine Block of Cyclic Nucleotide-gated Channels
por: Fodor, Anthony A., et al.
Publicado: (1997)

Topical local anesthesia: focus on lidocaine–tetracaine combination
por: Giordano, Davide, et al.
Publicado: (2015)

Improved efficacy of naproxen-loaded NLC for temporomandibular joint administration
por: Guilherme, Viviane A., et al.
Publicado: (2019)

Effect of Tetracaine on Intraocular Pressure in Normal and Hypertensive Rabbit Eyes
por: Sarchahi, Ali Asghar, et al.
Publicado: (2012)

Heated lidocaine/tetracaine patch for treatment of patellar tendinopathy pain
por: Gammaitoni, Arnold R, et al.
Publicado: (2013)

The effect of cold tetracaine on the severity of burning sensation upon instillation
por: Sansanayudh, Wiwan, et al.
Publicado: (2018)

Design, Synthesis, and Anticancer Evaluation of Novel Tetracaine Hydrazide-Hydrazones
por: Han, M. İhsan, et al.
Publicado: (2023)

Nanocarriers From Natural Lipids With In Vitro Activity Against Campylobacter jejuni
por: Ribeiro, Lígia Nunes de Morais, et al.
Publicado: (2021)

Spinal Anesthesia with Isobaric Tetracaine in Patients with Previous Lumbar Spinal Surgery
por: Kim, Soo Hwan, et al.
Publicado: (2009)

Neurotrophic Corneal Ulcer after Topical Tetracaine Abuse: Management Guidelines
por: Sedaghat, M R, et al.
Publicado: (2011)

Mechanisms Underlying the Strong Inhibition of Muscle-Type Nicotinic Receptors by Tetracaine
por: Cobo, Raúl, et al.
Publicado: (2018)

An Innovative Formulation Based on Nanostructured Lipid Carriers for Imatinib Delivery: Pre-Formulation, Cellular Uptake and Cytotoxicity Studies
por: Gundogdu, Evren, et al.
Publicado: (2022)

Formulation and in vitro characterization of domperidone loaded solid lipid nanoparticles and nanostructured lipid carriers
por: Thatipamula, RP., et al.
Publicado: (2011)

Ocular Formulation Based on Palmitoylethanolamide-Loaded Nanostructured Lipid Carriers: Technological and Pharmacological Profile
por: Puglia, Carmelo, et al.
Publicado: (2020)

Nanostructured lipid carriers (NLCs) as drug delivery platform: Advances in formulation and delivery strategies
por: Elmowafy, Mohammed, et al.
Publicado: (2021)

Tetracaine Reports a Conformational Change in the Pore of Cyclic Nucleotide–gated Channels
por: Fodor, Anthony A., et al.
Publicado: (1997)

Review of Lidocaine/Tetracaine Cream as a Topical Anesthetic for Dermatologic Laser Procedures
por: Alster, Tina
Publicado: (2013)

Excipient-excipient interactions in the development of nanocarriers: an innovative statistical approach for formulation decisions
por: Beraldo-de-Araújo, Viviane Lucia, et al.
Publicado: (2019)

Articaine in functional NLC show improved anesthesia and anti-inflammatory activity in zebrafish
por: Rodrigues da Silva, Gustavo H., et al.
Publicado: (2020)

Ribociclib Nanostructured Lipid Carrier Aimed for Breast Cancer: Formulation Optimization, Attenuating In Vitro Specification, and In Vivo Scrutinization
por: Sartaj, Ali, et al.
Publicado: (2022)

Formulation design, preparation, and in vitro and in vivo characterizations of β-Elemene-loaded nanostructured lipid carriers
por: Shi, Feng, et al.
Publicado: (2013)

Formulation of Menthol-Loaded Nanostructured Lipid Carriers to Enhance Its Antimicrobial Activity for Food Preservation
por: Piran, Parizad, et al.
Publicado: (2017)

Formulation And Evaluation Of Nanostructured Lipid Carriers (NLCs) Of 20(S)-Protopanaxadiol (PPD) By Box-Behnken Design
por: Kim, Min-Hwan, et al.
Publicado: (2019)

In Vitro Studies on Nasal Formulations of Nanostructured Lipid Carriers (NLC) and Solid Lipid Nanoparticles (SLN)
por: Costa, Cláudia Pina, et al.
Publicado: (2021)

Effects of Tetracaine on Voltage-activated Calcium Sparks in Frog Intact Skeletal Muscle Fibers
por: Hollingworth, Stephen, et al.
Publicado: (2006)

Differential effects of tetracaine on charge movements and Ca2+ signals in frog skeletal muscle
Publicado: (1988)

Effects of caffeine, tetracaine, and ryanodine on calcium-dependent oscillations in sheep cardiac Purkinje fibers
Publicado: (1985)

Erratum to: Review of Lidocaine/Tetracaine Cream as a Topical Anesthetic for Dermatologic Laser Procedures
por: Alster, Tina
Publicado: (2013)

Subunit and frequency-dependent inhibition of Acid Sensing Ion Channels by local anesthetic tetracaine
por: Leng, Tiandong, et al.
Publicado: (2013)

The effects and side effects of lidocaine tetracaine peel off on laser-assisted hair removal
por: Asilian, Ali, et al.
Publicado: (2014)

Pentadecapeptide BPC 157 shortens duration of tetracaine- and oxybuprocaine-induced corneal anesthesia in rats
por: Mirković, Ivan, et al.
Publicado: (2020)

The Autofluorescence Patterns of Acanthamoeba castellanii, Pseudomonas aeruginosa and Staphylococcus aureus: Effects of Antibiotics and Tetracaine
por: Peguda, Hari Kumar, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_rfd2c02jmesvmbd9arceerq2n4