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Ca(2+) imbalance caused by ERdj5 deletion affects mitochondrial fragmentation

The endoplasmic reticulum (ER) is the organelle responsible for the folding of secretory/membrane proteins and acts as a dynamic calcium ion (Ca(2+)) store involved in various cellular signalling pathways. Previously, we reported that the ER-resident disulfide reductase ERdj5 is involved in the ER-a...

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Detalles Bibliográficos
Autores principales: Yamashita, Riyuji, Fujii, Shohei, Ushioda, Ryo, Nagata, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8563984/
https://www.ncbi.nlm.nih.gov/pubmed/34728782
http://dx.doi.org/10.1038/s41598-021-99980-9