CCA-addition in the cold: Structural characterization of the psychrophilic CCA-adding enzyme from the permafrost bacterium Planococcus halocryophilus

CCA-adding enzymes are highly specific RNA polymerases that add and maintain the sequence C-C-A at tRNA 3‘-ends. Recently, we could reveal that cold adaptation of such a polymerase is not only achieved at the expense of enzyme stability, but also at the cost of polymerization fidelity. Enzymes from...

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Detalles Bibliográficos
Autores principales: de Wijn, Raphaël, Rollet, Kévin, Ernst, Felix G.M., Wellner, Karolin, Betat, Heike, Mörl, Mario, Sauter, Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8563995/
https://www.ncbi.nlm.nih.gov/pubmed/34765099
http://dx.doi.org/10.1016/j.csbj.2021.10.018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8563995/
https://www.ncbi.nlm.nih.gov/pubmed/34765099
http://dx.doi.org/10.1016/j.csbj.2021.10.018

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