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Genome Instability and Long Noncoding RNA Reveal Biomarkers for Immunotherapy and Prognosis and Novel Competing Endogenous RNA Mechanism in Colon Adenocarcinoma

Background: Long noncoding RNAs (lncRNAs) crucially modulate DNA damage responses/repair in cancer cells. However, the underlying regulatory role of genome integrity and its clinical value in colon adenocarcinoma (COAD) remains unclear. This study links genome instability to lncRNA using computation...

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Detalles Bibliográficos
Autores principales: Ren, Ziyuan, Wang, Zhonglin, Gu, Donghong, Ma, Hanchen, Zhu, Yan, Cai, Menghua, Zhang, Jianmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564000/
https://www.ncbi.nlm.nih.gov/pubmed/34746134
http://dx.doi.org/10.3389/fcell.2021.740455