Sirtuin 6 Protects Against Oxidative Stress and Vascular Dysfunction in Mice

Objective: Sirtuin deacetylases are major regulators of organismal aging, and while depletion of sirtuin 6 (SIRT6) in mice results in a profound progeroid phenotype, the role of SIRT6 in the regulation of vasomotor function is unknown. Thus, our objective was to test the hypothesis that reductions i...

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Detalles Bibliográficos
Autores principales: Greiten, Lawrence E., Zhang, Bin, Roos, Carolyn M., Hagler, Michael, Jahns, Fritz-Patrick, Miller, Jordan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564013/
https://www.ncbi.nlm.nih.gov/pubmed/34744793
http://dx.doi.org/10.3389/fphys.2021.753501

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564013/
https://www.ncbi.nlm.nih.gov/pubmed/34744793
http://dx.doi.org/10.3389/fphys.2021.753501

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