Cargando…

An ATX-LPA(6)-Gα(13)-ROCK axis shapes and maintains caudal vein plexus in zebrafish

Lysophosphatidic acid (LPA) is a potential regulator of vascular formation derived from blood. In this study, we utilized zebrafish as a model organism to monitor the blood vessel formation in detail. Zebrafish mutant of ATX, an LPA-producing enzyme, had a defect in the caudal vein plexus (CVP). Pha...

Descripción completa

Detalles Bibliográficos
Autores principales: Okasato, Ryohei, Kano, Kuniyuki, Kise, Ryoji, Inoue, Asuka, Fukuhara, Shigetomo, Aoki, Junken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564058/
https://www.ncbi.nlm.nih.gov/pubmed/34755093
http://dx.doi.org/10.1016/j.isci.2021.103254