Roles of RAGE/ROCK1 Pathway in HMGB1-Induced Early Changes in Barrier Permeability of Human Pulmonary Microvascular Endothelial Cell

BACKGROUND: High mobility group box 1 (HMGB1) causes microvascular endothelial cell barrier dysfunction during acute lung injury (ALI) in sepsis, but the mechanisms have not been well understood. We studied the roles of RAGE and Rho kinase 1 (ROCK1) in HMGB1-induced human pulmonary endothelial barri...

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Detalles Bibliográficos
Autores principales: Zhao, Meng-jiao, Jiang, Hao-ran, Sun, Jing-wen, Wang, Zi-ang, Hu, Bo, Zhu, Cheng-rui, Yin, Xiao-han, Chen, Ming-ming, Ma, Xiao-chun, Zhao, Wei-dong, Luan, Zheng-gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564108/
https://www.ncbi.nlm.nih.gov/pubmed/34745088
http://dx.doi.org/10.3389/fimmu.2021.697071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564108/
https://www.ncbi.nlm.nih.gov/pubmed/34745088
http://dx.doi.org/10.3389/fimmu.2021.697071

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