CD4+ T Cells Are Dispensable for Induction of Broad Heterologous HIV Neutralizing Antibodies in Rhesus Macaques

Induction of broadly neutralizing antibodies (bNAbs) is a major goal for HIV vaccine development. HIV envelope glycoprotein (Env)-specific bNAbs isolated from HIV-infected individuals exhibit substantial somatic hypermutation and correlate with T follicular helper (Tfh) responses. Using the VC10014...

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Detalles Bibliográficos
Autores principales: Sarkar, Sanghita, Spencer, David A., Barnette, Philip, Pandey, Shilpi, Sutton, William F., Basu, Madhubanti, Burch, Reuben E., Cleveland, John D., Rosenberg, Alexander F., Rangel-Moreno, Javier, Keefer, Michael C., Hessell, Ann J., Haigwood, Nancy L., Kobie, James J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564110/
https://www.ncbi.nlm.nih.gov/pubmed/34745131
http://dx.doi.org/10.3389/fimmu.2021.757811

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564110/
https://www.ncbi.nlm.nih.gov/pubmed/34745131
http://dx.doi.org/10.3389/fimmu.2021.757811

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