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LncRNA OIP5-AS1 Promotes the Autophagy-Related Imatinib Resistance in Chronic Myeloid Leukemia Cells by Regulating miR-30e-5p/ATG12 Axis

Background: Resistance to tyrosine kinase inhibitors (TKIs) in patients with chronic myeloid leukemia (CML) remains a problem in clinical treatment, and the mechanism has not been fully clarified. Autophagy can protect cancer cells under chemotherapeutic stimulation. Long noncoding RNAs (lncRNAs) ar...

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Detalles Bibliográficos
Autores principales: Dai, Hongdan, Wang, Jianming, Huang, Zhenglan, Zhang, Hui, Wang, Xin, Li, Qian, Feng, Wenli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564130/
https://www.ncbi.nlm.nih.gov/pubmed/34723728
http://dx.doi.org/10.1177/15330338211052150