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A CpG Methylation Signature as a Potential Marker for Early Diagnosis of Hepatocellular Carcinoma From HBV-Related Liver Disease Using Multiplex Bisulfite Sequencing

BACKGROUND: Aberrant methylation of CpG sites served as an epigenetic marker for building diagnostic, prognostic, and recurrence models for hepatocellular carcinoma (HCC). METHODS: Using Illumina 450K and EPIC Beadchip, we identified 34 CpG sites in peripheral blood mononuclear cell (PBMC) DNA that...

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Detalles Bibliográficos
Autores principales: Li, Kang, Song, Yi, Qin, Ling, Li, Ang, Jiang, Sanjie, Ren, Lei, Zang, Chaoran, Sun, Jianping, Zhao, Yan, Zhang, Yonghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564137/
https://www.ncbi.nlm.nih.gov/pubmed/34745991
http://dx.doi.org/10.3389/fonc.2021.756326