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The Relationship of APOE ε4, Race, and Sex on the Age of Onset and Risk of Dementia

Objective: To investigate whether APOE ε4 genotype—an established risk factor for dementia—is associated with earlier age at diagnosis in addition to increased risk overall and in secondary analysis by race and sex. Methods: We followed up 13,782 dementia-free individuals (n = 10,137 White, n = 3,64...

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Detalles Bibliográficos
Autores principales: Powell, Danielle S., Kuo, Pei-Lun, Qureshi, Riaz, Coburn, Sally B., Knopman, David S., Palta, Priya, Gottesman, Rebecca, Griswold, Michael, Albert, Marilyn, Deal, Jennifer A., Gross, Alden L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564142/
https://www.ncbi.nlm.nih.gov/pubmed/34744974
http://dx.doi.org/10.3389/fneur.2021.735036