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Non-Randomized Trial of Dornase Alfa for Acute Respiratory Distress Syndrome Secondary to Covid-19

BACKGROUND: The most severe cases of Coronavirus-Disease-2019 (COVID-19) develop into Acute Respiratory Distress Syndrome (ARDS). It has been proposed that oxygenation may be inhibited by extracellular deoxyribonucleic acid (DNA) in the form of neutrophil extracellular traps (NETs). Dornase alfa (Pu...

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Detalles Bibliográficos
Autores principales: Holliday, Zachary M., Earhart, Alexander P., Alnijoumi, Mohammed M., Krvavac, Armin, Allen, Lee-Ann H., Schrum, Adam G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564175/
https://www.ncbi.nlm.nih.gov/pubmed/34745093
http://dx.doi.org/10.3389/fimmu.2021.714833