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Enhanced Store-Operated Ca(2+) Signal of Small Intestinal Smooth Muscle Cells Accelerates Small Bowel Transit Speed in Type 1 Diabetic Mouse

Aims: The underlying mechanism of diabetic enteropathy, a common complication of type 1 diabetes, remains unclear. Store-operated Ca(2+) entry (SOCE) is a ubiquitous type of Ca(2+) influx involved in various cellular functions. Here, we show that SOCE-related stromal interaction molecule 1 (STIM1) a...

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Detalles Bibliográficos
Autores principales: Dai, Fang, Guo, Jizheng, Wang, Yang, Jiang, Tian, Chen, Hongbo, Hu, Ying, Du, Juan, Xia, Xianming, Zhang, Qiu, Shen, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564290/
https://www.ncbi.nlm.nih.gov/pubmed/34744757
http://dx.doi.org/10.3389/fphys.2021.691867