Interaction-Based Feature Selection Algorithm Outperforms Polygenic Risk Score in Predicting Parkinson’s Disease Status

Polygenic risk scores (PRS) aggregating results from genome-wide association studies are the state of the art in the prediction of susceptibility to complex traits or diseases, yet their predictive performance is limited for various reasons, not least of which is their failure to incorporate the eff...

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Detalles Bibliográficos
Autores principales: Cope, Justin L., Baukmann, Hannes A., Klinger, Jörn E., Ravarani, Charles N. J., Böttinger, Erwin P., Konigorski, Stefan, Schmidt, Marco F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564367/
https://www.ncbi.nlm.nih.gov/pubmed/34745218
http://dx.doi.org/10.3389/fgene.2021.744557

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564367/
https://www.ncbi.nlm.nih.gov/pubmed/34745218
http://dx.doi.org/10.3389/fgene.2021.744557

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