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Uncovering Key Metabolic Determinants of the Drug Interactions Between Trimethoprim and Erythromycin in Escherichia coli

Understanding interactions between antibiotics used in combination is an important theme in microbiology. Using the interactions between the antifolate drug trimethoprim and the ribosome-targeting antibiotic erythromycin in Escherichia coli as a model, we applied a transcriptomic approach for dissec...

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Detalles Bibliográficos
Autores principales: Qi, Qin, Angermayr, S. Andreas, Bollenbach, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564399/
https://www.ncbi.nlm.nih.gov/pubmed/34745067
http://dx.doi.org/10.3389/fmicb.2021.760017