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Living Dangerously: Protective and Harmful ER Stress Responses in Pancreatic β-Cells

Type 2 diabetes (T2D) is a growing cause of poor health, psychosocial burden, and economic costs worldwide. The pancreatic β-cell is a cornerstone of metabolic physiology. Insulin deficiency leads to hyperglycemia, which was fatal before the availability of therapeutic insulins; even partial deficie...

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Detalles Bibliográficos
Autores principales: Sharma, Rohit B., Landa-Galván, Huguet V., Alonso, Laura C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564401/
https://www.ncbi.nlm.nih.gov/pubmed/34711668
http://dx.doi.org/10.2337/dbi20-0033