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Lipid Droplets Protect Human β-Cells From Lipotoxicity-Induced Stress and Cell Identity Changes
Free fatty acids (FFAs) are often stored in lipid droplet (LD) depots for eventual metabolic and/or synthetic use in many cell types, such a muscle, liver, and fat. In pancreatic islets, overt LD accumulation was detected in humans but not mice. LD buildup in islets was principally observed after ro...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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American Diabetes Association
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564404/ https://www.ncbi.nlm.nih.gov/pubmed/34433630 http://dx.doi.org/10.2337/db21-0261 |