A Novel Mechanism of Endoplasmic Reticulum Stress‐ and c‐Myc‐Degradation‐Mediated Therapeutic Benefits of Antineurokinin‐1 Receptor Drugs in Colorectal Cancer

The neurokinin‐1 receptor (NK‐1R) antagonists are approved as treatment for chemotherapy‐associated nausea and vomiting in cancer patients. The emerging role of the substance P‐NK‐1R system in oncogenesis raises the possibility of repurposing well‐tolerated NK‐1R antagonists for cancer treatment. Th...

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Detalles Bibliográficos
Autores principales: Shi, Yue, Wang, Xi, Meng, Yueming, Ma, Junjie, Zhang, Qiyu, Shao, Gang, Wang, Lingfei, Cheng, Xurui, Hong, Xiangyu, Wang, Yong, Yan, Zhibin, Cao, Yihai, Kang, Jian, Fu, Caiyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564433/
https://www.ncbi.nlm.nih.gov/pubmed/34605226
http://dx.doi.org/10.1002/advs.202101936

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564433/
https://www.ncbi.nlm.nih.gov/pubmed/34605226
http://dx.doi.org/10.1002/advs.202101936

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