MHC-Optimized Peptide Scaffold for Improved Antigen Presentation and Anti-Tumor Response

Tumor Associated Antigens (TAAs) may suffer from an immunological tolerance due to expression on normal cells. In order to potentiate their immunogenicity, heteroclitic peptides (htcPep) were designed according to prediction algorithms. In particular, specific modifications were introduced in peptid...

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Detalles Bibliográficos
Autores principales: Tagliamonte, Maria, Mauriello, Angela, Cavalluzzo, Beatrice, Ragone, Concetta, Manolio, Carmen, Luciano, Antonio, Barbieri, Antonio, Palma, Giuseppe, Scognamiglio, Giosuè, Di Mauro, Annabella, Di Bonito, Maurizio, Tornesello, Maria Lina, Buonaguro, Franco M., Vitagliano, Luigi, Caporale, Andrea, Ruvo, Menotti, Buonaguro, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564487/
https://www.ncbi.nlm.nih.gov/pubmed/34745146
http://dx.doi.org/10.3389/fimmu.2021.769799

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564487/
https://www.ncbi.nlm.nih.gov/pubmed/34745146
http://dx.doi.org/10.3389/fimmu.2021.769799

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