Switched Aβ43 generation in familial Alzheimer’s disease with presenilin 1 mutation

Presenilin (PS) with a genetic mutation generates abundant β-amyloid protein (Aβ) 43. Senile plaques are formed by Aβ43 in the cerebral parenchyma together with Aβ42 at middle ages. These brains cause the early onset of Alzheimer’s disease (AD), which is known as familial Alzheimer’s disease (FAD)....

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Detalles Bibliográficos
Autores principales: Kakuda, Nobuto, Takami, Mako, Okochi, Masayasu, Kasuga, Kensaku, Ihara, Yasuo, Ikeuchi, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564532/
https://www.ncbi.nlm.nih.gov/pubmed/34728605
http://dx.doi.org/10.1038/s41398-021-01684-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564532/
https://www.ncbi.nlm.nih.gov/pubmed/34728605
http://dx.doi.org/10.1038/s41398-021-01684-1

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