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Cryo-EM structures and transport mechanism of human P5B type ATPase ATP13A2

Polyamines are important polycations that play critical roles in mammalian cells. ATP13A2 belongs to the orphan P5B adenosine triphosphatases (ATPase) family and has been established as a lysosomal polyamine exporter to maintain the normal function of lysosomes and mitochondria. Previous studies hav...

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Detalles Bibliográficos
Autores principales: Chen, Xudong, Zhou, Mingze, Zhang, Sensen, Yin, Jian, Zhang, Ping, Xuan, Xujun, Wang, Peiyi, Liu, Zhiqiang, Zhou, Boda, Yang, Maojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564547/
https://www.ncbi.nlm.nih.gov/pubmed/34728622
http://dx.doi.org/10.1038/s41421-021-00334-6