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SMAC/Diablo controls proliferation of cancer cells by regulating phosphatidylethanolamine synthesis

SMAC/Diablo, a pro‐apoptotic protein, yet it is overexpressed in several cancer types. We have described a noncanonical function for SMAC/Diablo as a regulator of lipid synthesis during cancer cell proliferation and development. Here, we explore the molecular mechanism through which SMAC/Diablo regu...

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Detalles Bibliográficos
Autores principales: Pandey, Swaroop Kumar, Paul, Avijit, Shteinfer‐Kuzmine, Anna, Zalk, Ran, Bunz, Uwe, Shoshan‐Barmatz, Varda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564633/
https://www.ncbi.nlm.nih.gov/pubmed/33794068
http://dx.doi.org/10.1002/1878-0261.12959