Cargando…
SMAC/Diablo controls proliferation of cancer cells by regulating phosphatidylethanolamine synthesis
SMAC/Diablo, a pro‐apoptotic protein, yet it is overexpressed in several cancer types. We have described a noncanonical function for SMAC/Diablo as a regulator of lipid synthesis during cancer cell proliferation and development. Here, we explore the molecular mechanism through which SMAC/Diablo regu...
Autores principales: | Pandey, Swaroop Kumar, Paul, Avijit, Shteinfer‐Kuzmine, Anna, Zalk, Ran, Bunz, Uwe, Shoshan‐Barmatz, Varda |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564633/ https://www.ncbi.nlm.nih.gov/pubmed/33794068 http://dx.doi.org/10.1002/1878-0261.12959 |
Ejemplares similares
-
Non-apoptotic activity of the mitochondrial protein SMAC/Diablo in lung cancer: Novel target to disrupt survival, inflammation, and immunosuppression
por: Pandey, Swaroop Kumar, et al.
Publicado: (2022) -
Silencing VDAC1 to Treat Mesothelioma Cancer: Tumor Reprograming and Altering Tumor Hallmarks
por: Pandey, Swaroop Kumar, et al.
Publicado: (2022) -
Pro-Apoptotic and Anti-Cancer Activity of the Vernonanthura Nudiflora Hydroethanolic Extract
por: Nadir, Almog, et al.
Publicado: (2023) -
Mitochondrial VDAC1 Silencing Leads to Metabolic Rewiring and the Reprogramming of Tumour Cells into Advanced Differentiated States
por: Arif, Tasleem, et al.
Publicado: (2018) -
VDAC1 at the Intersection of Cell Metabolism, Apoptosis, and Diseases
por: Shoshan-Barmatz, Varda, et al.
Publicado: (2020)