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EGFR transcription in non‐small‐cell lung cancer tumours can be revealed in ctDNA by cell‐free chromatin immunoprecipitation (cfChIP)

Determination of tumour‐specific transcription based on liquid biopsies possesses a large diagnostic and prognostic potential in non‐small cell lung cancer (NSCLC). Cell‐free DNA (cfDNA) packed in nucleosomes mirrors the histone modification profiles present in the cells of origin. H3 lysine 36 trim...

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Detalles Bibliográficos
Autores principales: Månsson, Christoffer Trier, Vad‐Nielsen, Johan, Meldgaard, Peter, Nielsen, Anders Lade, Sorensen, Boe Sandahl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564636/
https://www.ncbi.nlm.nih.gov/pubmed/34453867
http://dx.doi.org/10.1002/1878-0261.13093