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Dynamic changes in the T cell receptor repertoire during treatment with radiotherapy combined with an immune checkpoint inhibitor

Previous studies have indicated a synergistic effect between radiotherapy and immunotherapy. A better understanding of how this combination affects the immune system can help to clarify its role in the treatment of metastatic cancer. We performed T cell receptor (TCR) sequencing on 46 sequentially c...

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Detalles Bibliográficos
Autores principales: Öjlert, Åsa Kristina, Nebdal, Daniel, Snapkov, Igor, Olsen, Vibeke, Kidman, Joel, Greiff, Victor, Chee, Jonathan, Helland, Åslaug
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564644/
https://www.ncbi.nlm.nih.gov/pubmed/34402187
http://dx.doi.org/10.1002/1878-0261.13082