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Fluid shear stress activates YAP to promote epithelial–mesenchymal transition in hepatocellular carcinoma

Epithelial–mesenchymal transition (EMT) mediated by fluid shear stress (FSS) in the tumor microenvironment plays an important role in driving metastasis of the malignant tumor. As a mechanotransducer, Yes‐associated protein (YAP) is known to translocate into the nucleus to initiate transcription of...

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Detalles Bibliográficos
Autores principales: Yu, Hongchi, He, Jia, Su, Guanyue, Wang, Yuelong, Fang, Fei, Yang, Wenxing, Gu, Kaiyun, Fu, Naiyang, Wang, Yunbing, Shen, Yang, Liu, Xiaoheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564657/
https://www.ncbi.nlm.nih.gov/pubmed/34260811
http://dx.doi.org/10.1002/1878-0261.13061