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Fluid shear stress activates YAP to promote epithelial–mesenchymal transition in hepatocellular carcinoma
Epithelial–mesenchymal transition (EMT) mediated by fluid shear stress (FSS) in the tumor microenvironment plays an important role in driving metastasis of the malignant tumor. As a mechanotransducer, Yes‐associated protein (YAP) is known to translocate into the nucleus to initiate transcription of...
Autores principales: | Yu, Hongchi, He, Jia, Su, Guanyue, Wang, Yuelong, Fang, Fei, Yang, Wenxing, Gu, Kaiyun, Fu, Naiyang, Wang, Yunbing, Shen, Yang, Liu, Xiaoheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564657/ https://www.ncbi.nlm.nih.gov/pubmed/34260811 http://dx.doi.org/10.1002/1878-0261.13061 |
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