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A monoclonal antibody against annexin A2 targets stem and progenitor cell fractions in tumors

The involvement of cancer stem cells (CSCs) in driving tumor dormancy and drug resistance is well established. Most therapeutic regimens however are ineffective in targeting these regenerative populations. We report the development and evaluation of a monoclonal antibody, mAb150, which targets the m...

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Detalles Bibliográficos
Autores principales: Kalra, Rajkumar S., Soman, Gaurav S., Parab, Pradeep B., Mali, Avinash M., Varankar, Sagar S., Naik, Rutika R., Kamble, Swapnil C., Dhanjal, Jaspreet K., Bapat, Sharmila A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564672/
https://www.ncbi.nlm.nih.gov/pubmed/34715620
http://dx.doi.org/10.1016/j.tranon.2021.101257