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A monoclonal antibody against annexin A2 targets stem and progenitor cell fractions in tumors
The involvement of cancer stem cells (CSCs) in driving tumor dormancy and drug resistance is well established. Most therapeutic regimens however are ineffective in targeting these regenerative populations. We report the development and evaluation of a monoclonal antibody, mAb150, which targets the m...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564672/ https://www.ncbi.nlm.nih.gov/pubmed/34715620 http://dx.doi.org/10.1016/j.tranon.2021.101257 |