Strong acids induce amyloid fibril formation of β(2)-microglobulin via an anion-binding mechanism

Amyloid fibrils, crystal-like fibrillar aggregates of proteins associated with various amyloidoses, have the potential to propagate via a prion-like mechanism. Among known methodologies to dissolve preformed amyloid fibrils, acid treatment has been used with the expectation that the acids will degra...

Descripción completa

Detalles Bibliográficos
Autores principales: Yamaguchi, Keiichi, Hasuo, Kenshiro, So, Masatomo, Ikenaka, Kensuke, Mochizuki, Hideki, Goto, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564678/
https://www.ncbi.nlm.nih.gov/pubmed/34626645
http://dx.doi.org/10.1016/j.jbc.2021.101286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564678/
https://www.ncbi.nlm.nih.gov/pubmed/34626645
http://dx.doi.org/10.1016/j.jbc.2021.101286

Ejemplares similares