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Strong acids induce amyloid fibril formation of β(2)-microglobulin via an anion-binding mechanism
Amyloid fibrils, crystal-like fibrillar aggregates of proteins associated with various amyloidoses, have the potential to propagate via a prion-like mechanism. Among known methodologies to dissolve preformed amyloid fibrils, acid treatment has been used with the expectation that the acids will degra...
Autores principales: | Yamaguchi, Keiichi, Hasuo, Kenshiro, So, Masatomo, Ikenaka, Kensuke, Mochizuki, Hideki, Goto, Yuji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564678/ https://www.ncbi.nlm.nih.gov/pubmed/34626645 http://dx.doi.org/10.1016/j.jbc.2021.101286 |
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