Phosphorylation of human CEACAM1-LF by PKA and GSK3β promotes its interaction with β-catenin

CEACAM1-LF, a homotypic cell adhesion adhesion molecule, transduces intracellular signals via a 72 amino acid cytoplasmic domain that contains two immunoreceptor tyrosine-based inhibitory motifs (ITIMs) and a binding site for β-catenin. Phosphorylation of Ser503 by PKC in rodent CEACAM1 was shown to...

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Detalles Bibliográficos
Autores principales: Hu, Weidong, Bagramyan, Karine, Bhatticharya, Supriyo, Hong, Teresa, Tapia, Alonso, Wong, Patty, Kalkum, Markus, Shively, John E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564729/
https://www.ncbi.nlm.nih.gov/pubmed/34656562
http://dx.doi.org/10.1016/j.jbc.2021.101305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564729/
https://www.ncbi.nlm.nih.gov/pubmed/34656562
http://dx.doi.org/10.1016/j.jbc.2021.101305

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