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The non-coding genome in genetic brain disorders: new targets for therapy?

The non-coding genome, consisting of more than 98% of all genetic information in humans and once judged as ‘Junk DNA’, is increasingly moving into the spotlight in the field of human genetics. Non-coding regulatory elements (NCREs) are crucial to ensure correct spatio-temporal gene expression. Techn...

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Detalles Bibliográficos
Autores principales: Medico-Salsench, Eva, Karkala, Faidra, Lanko, Kristina, Barakat, Tahsin Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564736/
https://www.ncbi.nlm.nih.gov/pubmed/34414418
http://dx.doi.org/10.1042/EBC20200121