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Impact of Simulated Intestinal Fluids on Dissolution, Solution Chemistry, and Membrane Transport of Amorphous Multidrug Formulations

[Image: see text] The solution behavior and membrane transport of multidrug formulations were herein investigated in a biorelevant medium simulating fasted conditions. Amorphous multidrug formulations were prepared by the solvent evaporation method. Combinations of atazanavir (ATV) and ritonavir (RT...

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Detalles Bibliográficos
Autores principales: El Sayed, Mira, Alhalaweh, Amjad, Bergström, Christel A. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564758/
https://www.ncbi.nlm.nih.gov/pubmed/34613730
http://dx.doi.org/10.1021/acs.molpharmaceut.1c00480