Cargando…
Investigation of Praziquantel/Cyclodextrin Inclusion Complexation by NMR and LC-HRMS/MS: Mechanism, Solubility, Chemical Stability, and Degradation Products
[Image: see text] Praziquantel (PZQ) is a biopharmaceutical classification system (BCS) class II anthelmintic drug characterized by poor solubility and a bitter taste, both of which can be addressed by inclusion complexation with cyclodextrins (CD). In this work, a comprehensive investigation of pra...
Autores principales: | Špehar, Tatjana Kezele, Pocrnić, Marijana, Klarić, David, Bertoša, Branimir, Čikoš, Ana, Jug, Mario, Padovan, Jasna, Dragojević, Snježana, Galić, Nives |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564759/ https://www.ncbi.nlm.nih.gov/pubmed/34670371 http://dx.doi.org/10.1021/acs.molpharmaceut.1c00716 |
Ejemplares similares
-
Chiral Separation of Beta-blockers by High-performance Liquid Chromatography and Determination of Bisoprolol Enantiomers in Surface Waters
por: Pocrnić, Marijana, et al.
Publicado: (2020) -
Teucrium montanum L.—Unrecognized Source of Phenylethanoid Glycosides: Green Extraction Approach and Elucidation of Phenolic Compounds via NMR and UHPLC-HR MS/MS
por: Mandura Jarić, Ana, et al.
Publicado: (2023) -
Screening of Novel Antimicrobial Diastereomers of Azithromycin–Thiosemicarbazone Conjugates: A Combined LC-SPE/Cryo NMR, MS/MS and Molecular Modeling Approach
por: Habinovec, Iva, et al.
Publicado: (2022) -
Interactions of Aminopropyl–Azithromycin Derivatives, Precursors in the Synthesis of Bioactive Macrozones, with E. coli Ribosome: NMR and Docking Studies
por: Mikulandra, Ivana, et al.
Publicado: (2021) -
Differentiation of industrial hemp strains by their cannabinoid and phenolic compounds using LC × LC-HRMS
por: Montero, Lidia, et al.
Publicado: (2022)