Enhancer RNAs Mediate Estrogen-Induced Decommissioning of Selective Enhancers by Recruiting ERα and Its Cofactor

The function of enhancer RNAs (eRNAs) in transcriptional regulation remains obscure. By analyzing the genome-wide nascent transcript profiles in breast cancer cells, we identify a special group of eRNAs that are essential for estrogen-induced transcriptional repression. Using eRNAs of TM4SF1 and EFE...

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Detalles Bibliográficos
Autores principales: Yang, Mei, Lee, Ji Hoon, Zhang, Zhao, De La Rosa, Richard, Bi, Mingjun, Tan, Yuliang, Liao, Yiji, Hong, Juyeong, Du, Baowen, Wu, Yanming, Scheirer, Jessica, Hong, Tao, Li, Wei, Fei, Teng, Hsieh, Chen-Lin, Liu, Zhijie, Li, Wenbo, Rosenfeld, Michael G., Xu, Kexin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564762/
https://www.ncbi.nlm.nih.gov/pubmed/32579929
http://dx.doi.org/10.1016/j.celrep.2020.107803

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564762/
https://www.ncbi.nlm.nih.gov/pubmed/32579929
http://dx.doi.org/10.1016/j.celrep.2020.107803

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