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Epithelial stem cell homeostasis in Meibomian gland development, dysfunction, and dry eye disease

Dry eye disease affects over 16 million adults in the US, and the majority of cases are due to Meibomian gland dysfunction. Unfortunately, the identity of the stem cells involved in Meibomian gland development and homeostasis is not well elucidated. Here, we report that loss of Krox20, a zinc finger...

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Detalles Bibliográficos
Autores principales: Tchegnon, Edem, Liao, Chung-Ping, Ghotbi, Elnaz, Shipman, Tracey, Wang, Yong, McKay, Renee M., Le, Lu Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564894/
https://www.ncbi.nlm.nih.gov/pubmed/34499624
http://dx.doi.org/10.1172/jci.insight.151078