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Preimplantation factor modulates oligodendrocytes by H19-induced demethylation of NCOR2

Failed or altered gliogenesis is a major characteristic of diffuse white matter injury in survivors of premature birth. The developmentally regulated long noncoding RNA (lncRNA) H19 inhibits S-adenosylhomocysteine hydrolase (SAHH) and contributes to methylation of diverse cellular components, such a...

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Detalles Bibliográficos
Autores principales: Spinelli, Marialuigia, Boucard, Celiné, Ornaghi, Sara, Schoeberlein, Andreina, Irene, Keller, Coman, Daniel, Hyder, Fahmeed, Zhang, Longbo, Haesler, Valérie, Bordey, Angelique, Barnea, Eytan, Paidas, Michael, Surbek, Daniel, Mueller, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564895/
https://www.ncbi.nlm.nih.gov/pubmed/34676826
http://dx.doi.org/10.1172/jci.insight.132335