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Increased IL-6 expression precedes reliable viral detection in the rhesus macaque brain during acute SIV infection

Knowledge of immune activation in the brain during acute HIV infection is crucial for the prevention and treatment of HIV-associated neurological disorders. We determined regional brain (basal ganglia, thalamus, and frontal cortex) immune and virological profiles at 7 and 14 days post infection (dpi...

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Detalles Bibliográficos
Autores principales: Gopalakrishnan, Raja Mohan, Aid, Malika, Mercado, Noe B., Davis, Caitlin, Malik, Shaily, Geiger, Emma, Varner, Valerie, Jones, Rhianna, Bosinger, Steven E., Piedra-Mora, Cesar, Martinot, Amanda J., Barouch, Dan H., Reeves, R. Keith, Tan, C. Sabrina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564899/
https://www.ncbi.nlm.nih.gov/pubmed/34676832
http://dx.doi.org/10.1172/jci.insight.152013