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Dysregulated overexpression of Sox9 induces fibroblast activation in pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a fatal fibrotic lung disease associated with unremitting fibroblast activation including fibroblast-to-myofibroblast transformation (FMT), migration, resistance to apoptotic clearance, and excessive deposition of extracellular matrix (ECM) proteins in the dist...

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Detalles Bibliográficos
Autores principales: Gajjala, Prathibha R., Kasam, Rajesh K., Soundararajan, Divyalakshmi, Sinner, Debora, Huang, Steven K., Jegga, Anil G., Madala, Satish K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564901/
https://www.ncbi.nlm.nih.gov/pubmed/34520400
http://dx.doi.org/10.1172/jci.insight.152503