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Dysregulated overexpression of Sox9 induces fibroblast activation in pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a fatal fibrotic lung disease associated with unremitting fibroblast activation including fibroblast-to-myofibroblast transformation (FMT), migration, resistance to apoptotic clearance, and excessive deposition of extracellular matrix (ECM) proteins in the dist...
Autores principales: | Gajjala, Prathibha R., Kasam, Rajesh K., Soundararajan, Divyalakshmi, Sinner, Debora, Huang, Steven K., Jegga, Anil G., Madala, Satish K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564901/ https://www.ncbi.nlm.nih.gov/pubmed/34520400 http://dx.doi.org/10.1172/jci.insight.152503 |
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