IL-21 enhances influenza vaccine responses in aged macaques with suppressed SIV infection

Natural aging and HIV infection are associated with chronic low-grade systemic inflammation, immune senescence, and impaired antibody responses to vaccines such as the influenza (flu) vaccine. We investigated the role of IL-21, a CD4(+) T follicular helper cell (Tfh) regulator, on flu vaccine antibo...

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Detalles Bibliográficos
Autores principales: Kvistad, Daniel, Pallikkuth, Suresh, Sirupangi, Tirupataiah, Pahwa, Rajendra, Kizhner, Alexander, Petrovas, Constantinos, Villinger, Francois, Pahwa, Savita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564910/
https://www.ncbi.nlm.nih.gov/pubmed/34491910
http://dx.doi.org/10.1172/jci.insight.150888

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564910/
https://www.ncbi.nlm.nih.gov/pubmed/34491910
http://dx.doi.org/10.1172/jci.insight.150888

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