Trauma-induced heme release increases susceptibility to bacterial infection

Infection is a common complication of major trauma that causes significantly increased morbidity and mortality. The mechanisms, however, linking tissue injury to increased susceptibility to infection remain poorly understood. To study this relationship, we present a potentially novel murine model in...

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Detalles Bibliográficos
Autores principales: Lee, Ghee Rye, Gallo, David, Alves de Souza, Rodrigo W., Tiwari-Heckler, Shilpa, Csizmadia, Eva, Harbison, James D., Shankar, Sidharth, Banner-Goodspeed, Valerie, Yaffe, Michael B., Longhi, Maria Serena, Hauser, Carl J., Otterbein, Leo E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564912/
https://www.ncbi.nlm.nih.gov/pubmed/34520397
http://dx.doi.org/10.1172/jci.insight.150813

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564912/
https://www.ncbi.nlm.nih.gov/pubmed/34520397
http://dx.doi.org/10.1172/jci.insight.150813

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