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Trauma-induced heme release increases susceptibility to bacterial infection
Infection is a common complication of major trauma that causes significantly increased morbidity and mortality. The mechanisms, however, linking tissue injury to increased susceptibility to infection remain poorly understood. To study this relationship, we present a potentially novel murine model in...
Autores principales: | Lee, Ghee Rye, Gallo, David, Alves de Souza, Rodrigo W., Tiwari-Heckler, Shilpa, Csizmadia, Eva, Harbison, James D., Shankar, Sidharth, Banner-Goodspeed, Valerie, Yaffe, Michael B., Longhi, Maria Serena, Hauser, Carl J., Otterbein, Leo E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564912/ https://www.ncbi.nlm.nih.gov/pubmed/34520397 http://dx.doi.org/10.1172/jci.insight.150813 |
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