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ANT2 drives proinflammatory macrophage activation in obesity

Macrophage proinflammatory activation is an important etiologic component of the development of insulin resistance and metabolic dysfunction in obesity. However, the underlying mechanisms are not clearly understood. Here, we demonstrate that a mitochondrial inner membrane protein, adenine nucleotide...

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Detalles Bibliográficos
Autores principales: Moon, Jae-Su, da Cunha, Flavia Franco, Huh, Jin Young, Andreyev, Alexander Yu, Lee, Jihyung, Mahata, Sushil K., Reis, Felipe C.G., Nasamran, Chanond A., Lee, Yun Sok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564915/
https://www.ncbi.nlm.nih.gov/pubmed/34676827
http://dx.doi.org/10.1172/jci.insight.147033