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Circular RNA circ-ERBB2 promotes HER2-positive breast cancer progression and metastasis via sponging miR-136-5p and miR-198

BACKGROUND: Circular RNAs (circRNAs) are pivotal regulators of various human cancers and circ-ERBB2 is abnormally expressed in breast cancer cells. However, the role and mechanism of circ-ERBB2 in HER2-positive breast cancer are still unknown. METHODS: The circ-ERBB2 expressions in the tumor tissues...

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Detalles Bibliográficos
Autores principales: Zhong, Jin-xiu, Kong, Yun-yuan, Luo, Rong-guang, Xia, Guo-jin, He, Wen-xing, Chen, Xue-zhong, Tan, Wei-wei, Chen, Qing-jie, Huang, Yu-yin, Guan, Yan-xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564996/
https://www.ncbi.nlm.nih.gov/pubmed/34732216
http://dx.doi.org/10.1186/s12967-021-03114-8