Downregulation of miR-223 promotes HMGB2 expression and induces oxidative stress to activate JNK and promote autophagy in an in vitro model of acute lung injury

BACKGROUND: Excessive autophagic activity in alveolar epithelial cells is one of the main causes of acute lung injury (ALI), but the underlying molecular mechanism has not been fully elucidated. Previous studies have shown that microRNAs (miRs) are involved in regulating autophagy in several disease...

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Detalles Bibliográficos
Autores principales: Tan, Hao-Yu, Qing, Bei, Luo, Xian-Mei, Liang, Heng-Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565047/
https://www.ncbi.nlm.nih.gov/pubmed/34732212
http://dx.doi.org/10.1186/s12950-021-00295-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565047/
https://www.ncbi.nlm.nih.gov/pubmed/34732212
http://dx.doi.org/10.1186/s12950-021-00295-3

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